Parietal cells in the stomach produce which crucial factor?

Parietal cells in the stomach produce which crucial factor?

• A. Chief cells
• B. Parietal cells
• C. G cells
• D. Enteroendocrine cells

Answer: (B)

Parietal cells are responsible for producing intrinsic factor, a glycoprotein essential for vitamin B12 absorption in the terminal ileum. Without intrinsic factor, you can develop pernicious anemia due to impaired B12 uptake. These cells also secrete hydrochloric acid to create the acidic environment of the stomach, which helps digestion. The other cell types mentioned have different secretions: chief cells produce pepsinogen, G cells secrete gastrin to stimulate acid secretion, and enteroendocrine cells release various hormones. So the crucial factor produced by these parietal cells is intrinsic factor.

Parietal cells are responsible for producing intrinsic factor, a glycoprotein essential for vitamin B12 absorption in the terminal ileum. Without intrinsic factor, you can develop pernicious anemia due to impaired B12 uptake. These cells also secrete hydrochloric acid to create the acidic environment of the stomach, which helps digestion. The other cell types mentioned have different secretions: chief cells produce pepsinogen, G cells secrete gastrin to stimulate acid secretion, and enteroendocrine cells release various hormones. So the crucial factor produced by these parietal cells is intrinsic factor.